W325201

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W325201

 

β-Alanine

≥98%

Synonym:β-Ala, 3-Aminopropionic acid
CAS Number:107-95-9
Linear Formula:NH2CH2CH2COOH
Molecular Weight:89.09
FEMA Number:3252
Beilstein Registry Number:906793
EC Number:203-536-5
MDL number:MFCD00008200
PubChem Substance ID:24901588
Flavis number:17.001

Related Products

Description

Biochem/physiol ActionsEndogenous β-amino acid that is a nonselective agonist at glycine receptors and a ligand for the G protein-coupled orphan receptor, TGR7 (MrgD). β-alanine flux plays a cytoprotective role by supporting the osmotic stability of marine organisms, preimplantation mouse embryos and mammalian cells exposed to hypoxic stress.

Properties

gradeNI
assay≥98%
mp202 °C (dec.)(lit.)
Organolepticfruity; sweet

Safety

Personal Protective EquipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
WGK Germany3

References

referenceHoeger, U., and Abe, H., β-Alanine and other free amino acids during salinity adaptation of the polychaete Nereis japonica. Comp. Biochem. Physiol. 137, 161-171, (2004)
 Hammer, M.A., and Baltz, J.M., β-alanine but not taurine can function as an organic osmolyte in preimplantation mouse embryos. Mol. Reprod. Dev. 66, 153-161, (2003)
 Vairetti, M., et al., β-alanine protection against hypoxic liver injury in the rat. Biochim. Biophys. Acta 1587, 83-91, (2002)
 Shinohara, T., et al., Identification of a G protein-coupled receptor specifically responsive to β-alanine. J. Biol. Chem. 279, 23559-23564, (2004)
 Pullan, L.M., and Powel, R.J., Comparison of binding at strychnine-sensitive (inhibitory glycine receptor) and strychnine-insensitive (N-methyl-D-aspartate receptor) glycine binding sites. Neurosci. Lett. 148, 199-201, (1992)
MerckMerck 13,204
BeilsteinBeil. 4,IV,2526
FieserFieser 1,16 / Fieser 5,6 / Fieser 6,10 / Fieser 17,3
 Corp MSDS 1 (1), 84:D / FT-IR 1 (1), 572:A / FT-IR 2 (1), 916:D / FT-NMR 1 (1), 877:A / Fenaroli, 17 / IR-Spectra (2), 305:C / IR-Spectra (3), 342:C / NMR-Reference 2 (1), 486:C / RegBook 1 (1), 657:N / Sigma FT-IR 1 (1), 19:C / Structure Index 1, 97:A:5